目的 探讨星形细胞瘤播散性皮 层抑制的MR扩散加权成像(DWI)与病理学 特征的相关性。方法 采用回顾性研究方 法，2012年9月到2016年2月选择在我院诊 治的经手术病理证实的星形细胞瘤患者 84例，病理分级为低级别星形细胞瘤30 例(WHO Ⅰ级10例，WHOⅡ级20例)，高级 别星形细胞瘤患者54例(WHOⅢ级44例， WHOⅣ级10例)，都进行常规MRI检查与播 散性皮层抑制的MR DWI检查分析。结果 MRI常规检查显示低级别星形细胞瘤呈等 长T1、T2信号的结节或肿块影，瘤周无明 显水肿带，边界清晰，无明显占位效应； 高级别星形细胞瘤呈稍长T1、T2信号结节 影或肿块影，瘤周水肿带明显，占位效应 明显，边界模糊；经过判定，MRI对于星 形细胞瘤的病理分级诊断敏感性、特异 性、准确性为93.3%、90.7%、91.7%。播 散性皮层抑制的MR DWI显示低级与高级星 形细胞瘤相比，前者瘤体和瘤周的rADC、 ADC值均要高一些，对比差异都有统计学 意义(P<0.05)。结论 星形细胞瘤播散性 皮层抑制的MR扩散加权成像能有效反应病 理分级情况，能够提供更多的功能信息， 提高诊断率，是对常规MRI检查的有益补 充，有很好的应用价值。

Objective To study the correlation between MR diffusion weighted imaging (DWI) and pathologic features of disseminated cortical inhibition in astrocytoma. Methods Used retrospective study method, From September 2012 to February 2016 in our hospital, 84 cases with surgically and pathologically proved astrocytoma patients were selected for treatment that included pathological classification for low grade astrocytoma in 30 cases (10 cases of WHO grade Ⅰ, 20 cases of WHO grade Ⅱ), pathological classification for high-grade astrocytoma in 54 cases (44 cases of WHO grade Ⅲ, 10 cases of who grade Ⅳ). All cases were given conventional MRI and spread of cortical inhibition of MR diffusion-weighted imaging (DWI) analysis. Results MRI routine examination display low grade astrocytomas were showed isometric T1 and T2 signal nodules or masses, without peritumoral edema zone, clear boundary and were no obvious space occupying effect; high grade astrocytoma were showed slightly long T1, T2 signal nodules shadow or masses, peritumoral edema with significant and were obvious mass effect, fuzzy boundaries. After judging, MRI for astrocytic tumor pathological diagnosis sensitivity, specific and accuracy were 93.3%, 90.7% and 91.7%. MR DWI spreading cortical depression showed that the tumors and peritumoral ADC and rADC values in the low grade astrocytoma were significantly higher than that of high-grade astrocytomas, the difference were statistically significant (P<0.05). Conclusion Astrocytoma spreading cortical inhibition of MR diffusion weighted imaging can effectively reaction pathologic grade, it able to provide more information about the function of, improve the accuracy of diagnosis is a useful supplement for conventional MRI that has good application values.