论著-头颈部
CT及MRI在神经鞘瘤 诊治中应用研究
作者:肖日国1 吴佩红2 许晓杰3
所属单位:1.江苏省泰兴市第三人民医院CT室 2.江苏省泰兴市第三人民医院病理 科 (江苏 泰兴 225400) 3.江苏省泰兴市人民医院CT室 (江苏 泰兴 225400)
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目的 观察神经鞘瘤的计算机断 层扫描(CT)及磁共振成像(MRI)临床表 现,并分析比较两者在该病诊治中的应用 价值。方法 回顾性分析2009年3月-2014 年7月我院肿瘤外科收治的经手术病例证 实24例肝门部胆管神经鞘瘤患者临床资 料,对所有病例患者手术病理神经鞘瘤患 者MRI及CT影像学表现进行分析并比较, 并对两种诊断方法的应用价值进行评估。 结果 22例为单发病灶,2例有2个病灶, 共26个病灶;24个囊实性肿块病灶,2个 实性肿块病灶。CT平扫显示可见肝门区或 其上方及胰颈部上方呈类圆形、椭圆形或 稍低密度肿块,边界清晰,内可见低密度 囊性区;MRI扫描可见病灶实性部位T1WI 表现稍低或等信号,T2WI表现为等或稍高 信号;增强扫描呈不均匀性或进行性延迟 强化,坏死囊变区不强化;且CT及MRI均 可清晰将病灶周围完整包膜显示出来,且 边界清晰;病例检查显示肿块有完整包 膜,瘤细胞以梭形为主要特征。结论 CT 及MRI在神经鞘瘤中诊断均有较高应用价 值,其中肝门部肝管神经鞘瘤有特征性影 像学表现,CT及MRI对其均有较好的定位 诊断价值,为其临床诊治提供科学理论依 据。
Objective To observe the clinical manifestations of computed tomography (CT) and magnetic resonance imaging (MRI) for schwannoma and to analyze and compared the application value of the two in the diagnosis and treatment of the disease. Methods The clinical data of 24 patients with hilar bile duct schwannomaconfirmed by surgery and pathology who were treated in the department of surgical oncology in our hospital between March 2009 and July 2014 were retrospectively analyzed. The manifestations of MRI and CT of patients with surgical and pathological schwannoma were analyzed and compared, and the application value of the two diagnostic methods was evaluated.Results Twenty-two cases were single lesions, 2 cases had 2 lesions, a total of 26 lesions.Twentyfour were cystic solid lesions, and 2 were solid lesions. CT plain scan showed that there was round, oval or slightly low density mass with clear boundaries and low-density cystic areain hepatic hilar region, its upper region and top of the the pancreas;MRI scan showed that the solid part of the lesions manifested slightly lower or equal signal on T1WI andequal or slightly higher signal on T2WI. Enhanced scan showed inhomogeneous or progressive delayed enhancement, and no enhancement in necrotic cystic area. Both of CT and MRI can clearly show the whole surrounding of the lesions, and the boundaries were clear. The cases showed that the tumorswere with complete capsule, and the tumor cells were spindle shaped. Conclusion Both of CT and MRI is of high application value in diagnosis of schwannoma, and the hilar hepatic duct schwannomas are with characteristic imaging features. CT and MRI can better localize and diagnose, providing scientific theory basis for clinical diagnosis and treatment.
【关键词】神经鞘瘤;计算机断层扫描; 磁共振成像
【中图分类号】R739.4
【文献标识码】A
【DOI】 10.3969/j.issn.1672- 5131.2016.10.042
前言
神经鞘瘤又称为许旺氏瘤,为一种起源于外周运动神经、感觉神 经及脑神经鞘膜许旺细胞良性肿瘤,多见于脑神经、脊神经,较少发 生于舌根、四肢、纵隔、肺内或胸壁区外周神经[1];由于发生于少见 部位的神经鞘瘤术前易误诊,术中易将肿瘤连带神经干一起切除,引 发医源性神经损伤,对患者健康造成不可弥补的伤害,因而及时诊治 刻不容缓[2]。神经鞘瘤多发病于30~40岁中年人,早期无明显临床特 征,且生长缓慢,随着肿瘤逐渐增大才逐渐表现出临床症状,因而术 前较难作出准确定性诊断[3]。随着影像学技术在临床中应用的不断进 展,其中MRI及CT在神经鞘瘤中的诊断有着重要作用,特别是在使用对 比增强剂后优势更加明显,两者已被广泛应用于全身各部位神经鞘瘤 的诊断及评估中[4]。为科学比较CT级MRI在肝门部胆管神经鞘瘤诊治中 的应用价值,回顾性分析2009年3月~2014年7月我院肿瘤外科收治的 经手术病例证实的24例肝门部胆管神经鞘瘤患者CT及MRI影像学临床资 料,为神经鞘瘤合理治疗提供理论依据。
中国CT和MRI杂志
第14卷, 第 10 期
2016年10月
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