摘要
目的 探讨MRI判断星形胶质细 胞瘤(AG)术前分级的准确性及复发患者 的MRI征象特点。方法 选取68例AG患者 为研究对象,以手术病理检查结果为 依据,评估MRI对AG患者术前分级诊断 的准确性。术后行为期1年的随访,分 析复发患者的MRI征象。结果 术前MRI 检查对AG患者肿瘤分级的正确评估率为 94.1%(64/68),其中WHOⅠ-Ⅳ级的准确率 分别为86.7%(13/15)、95.0%(19/20)、 96.3%(26/27)和100.0%(6/6)。术后1 年的跟踪随访确诊复发9人,复发率为 13.2%;MRI检查见13个复发灶,信号均匀 1个(7.7%),信号不均匀12个(92.3%); 无强化表现0个(0.0%),结节状强化1 个(7.7%),片状强化2个(15.4%),花 环状强化9个(69.2%),团块状强化1个 (7.7%);瘤周轻度水肿1例(7.7%), 中度水肿5例(38.5%),重度水肿7例 (53.8%)。结论 MRI检查在AG患者术前分 级及术后复发评估中均可发挥积极作用。
Objective To investigate the accuracy of MRI in preoperative grading of astrocytoma (AG) and MRI findings of recurrent patients. Methods 68 patients with AG were selected as the study subjects. Based on the surgical and pathological examination, the accuracy of MRI in diagnosis of preoperative grading of AG was evaluated. The patients were follow up for 1 year after operation. The MRI findings of recurrent patients were analyzed. Results The correct evaluation rate of MRI in tumor grading of AG was 94.1% (64/68) and the accuracy rates in WHO grade I - IV were 86.7% (13/15), 95% (19/20), 96.3% (26/27) and 100.0% (6/6) respectively. After 1 year of follow-up, there were 9 recurrent patients and the recurrence rate was 13.2%. MRI examination showed 13 recurrence foci, 1 homogeneous signal (7.7%) and 12 inhomogeneous (92.3%); There was no enhancement in 0(0.0%), nodular enhancement in 1(7.7%), patchy enhancement in 2 (15.4%), garland-like enhancement in 9 (69.2%) and mass like enhancement in 1 (7.7%). There was 1 case with mild edema around tumor (7.7%), 5 cases with moderate peritumoral edema (38.5%) and 7 cases with severe edema (53.8%). Conclusion MRI examination can play an active role in the preoperative grading and postoperative recurrence evaluation of AG.
【关键词】MRI;星形胶质细胞瘤;术前 分级;准确性;复发;MRI征象
【中图分类号】R246.5
【文献标识码】A
【DOI】 10.3969/j.issn.1672- 5131.2016.10.006
前言
星形胶质细胞瘤(astrocytoma, AG)是胶质瘤的常见类型之一, 发病率约占胶质瘤的75%~80%,男性发病显著高于女性,且多发生于 大脑额叶和颞叶部位,及时有效的手术干预虽能有效抑制病情发展, 但受患者年龄、病程、病理分级、术式、术后瘤体残留情况等因素影 响[1],部分患者术后仍存在一定复发风险,需引起临床重视。随着影 像技术的普及与应用,MRI检查被应用于越来越多疾病的临床诊疗中, 获得理想的应用效果。本次研究为探讨MRI在AG患者术前分级及术后复 发评估中的临床应用价值,选取68例确诊患者为研究对象,现报告如 下。
中国CT和MRI杂志
第14卷, 第 10 期
2016年10月
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