Objective To compare the effects of enteral nutrition and parenteral nutrition for the early support of patients with severe acute stroke and dysphagia. Methods A total of 100 patients with dysphagia and severe acute stroke were selected from February 2011 to February 2013,who were randomly divided into two groups.50 patients were given enteral nutrition support treatment as the observation group, and the other 50 patients were given parenteral nutrition support treatment as the control group.The course of treatment was 3 weeks. Nutrition index and complications were compared between two groups before and after treatment. Results After treatment ,serum albumin and hemoglobin in the observation group were significantly higher than those in the control group,the differences were statistically significant (P<0.05); Complication rate in the observation group was significantly lower than that in the control group. The difference was statistically significant(p<0.05). Conclusion Early enteral nutrition support therapy for patients with serve acute stroke combined with dysphagia can significantly improve survival rate and decrease the incidence of physical-disability and decease.