Objective To explore and analyze the effect of nursing intervention on blood pressure control in hypertensive patients. Methods 100 patients with hypertension treated in our hospital from September 2014 to September 2016 were divided into group A (n=53) and group B (n=47) according to the order of hospital admission. Patients in group A and B Were given routine care, group A patients with integrated care. The blood pressure control and nursing satisfaction were compared between the two groups. Results There was no significant difference in the blood pressure before and after nursing intervention between the two groups (P>0.05). The blood pressure of the two groups was superior to that before the nursing intervention, the difference was statistically significant (P<0.05). The blood pressure of group A was better than that of group B, and the difference was statistically significant (P<0.05). The nursing satisfaction of group A was better than that of group B, the difference was statistically significant (P<0.05). Conclusion The comprehensive nursing intervention of hypertension patients is very effective, can control the blood pressure of patients well, and can improve the nursing satisfaction, it is worth to popularize.