Clinical Effect of Tacrolimus in Treating Elderly Steriod-resistant Nephrotic Syndrome
Author：WANG Shen-wei
affiliation：Department of Nephrology, Xuchang Central Hospital, Xuchang 461000, Henan Province, China
PDFAbstract
Objective To investigate the clinic effect of tacrolimus in treating steriod-resistant NS. Methods 60 cases with steriodresistant NS in our hospital from October 2015 to October 2016 were selected and divided into control group and observation group, control group was given cyclophosphamide and observation group was given tacrolimus. Compare the clinic effect of the two groups. Results After different treatment methods, total efficiency of observation group (96.67%) was higher than control group (60.00%). TC and 24h PRO of control group [(5.98±1.92)mmol/L, (2.97±0.32) g/24h]were higher than observation group [(4.27±2.01)mmol/L, (0.81±0.24)g/24h]. Albumin values of control group [(36.17±1.13)mmol/L] was lower than observation group [(46.99±1.04)mmol/L], the difference was statistically significanct (P<0.05). Conclusion The application of tacrolimus in treating steriod-resistant NS can improve renal function and is worthy of wide application.
【Keyword】Hormone; Resistant; NS; Tacrolimus; Clinic Effect
【Chart number】R692
【Document Identification Number】A
【DOI】10.3969/j.issn.1009-3257.2017.02.021
Journal of Rare Diseases
th24Volume， th 2 Issue
2019Year11Month
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