Head and Neck Imaging

Clinical Effect of Lamotrigine Combined with Acrylic Acid in Treatment of Patients with Epilepsy

Author:HAO Pei.

affiliation:Department of Neurology, The People's Hospital of Xinzheng City, Xinzheng 451100, Henan Province, China

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Abstract

Objective To study and analyze the clinical effects of lamotrigine combined with acrylic acid in treatment of patients with epilepsy. Methods From June 2015 to February 2017, 98 cases of patients with epilepsy received diagnosis and treatment in our hospital were selected in this study, which were divided into the study group and the control group by the random way with 49 cases in each group. The study group were implemented the lamotrigine combined with valproate treatment, while the control group were treated with valproic acid only. Then, the clinical effect of two groups of patients were observed and analyzed. Results All the patients were treated, and the clinical effect between the evaluation and analysis group showed that the study group was significantly higher than the control group (95.92% vs.79.59%, P<0.05). And the adverse reactions of the patients were observed and compared, the study group were significantly decreased than that in the control group (6.12% vs. 22.45%, P<0.05). Conclusion The implementation of lamotrigine combined with valproate therapy for patients with epilepsy, which it have good clinical effect.

【Keyword】Epilepsy; Lamotrigine; Valproic Acid; Clinical Effect

【Chart number】R453

【Document Identification Number】A

【DOI】10.3969/j.issn.1009-3257.2018.01.006