Objective To study the application of programmed nursing in the perioperative period of patients with high myopia cataract. Methods 120 patients with high myopia cataract in the hospital from September 2016 to September 2017 were selected and divided into two groups according to the random number table method. Control group was given routine nursing, and observation group was treated with programmed nursing on the basis of control group. The level of uncorrected visual acuity was measured in the two groups after operation, and the occurrence of postoperative complications was counted in the two groups. And the nursing satisfaction was counted in the two groups. Results After operation, the improvement of uncorrected visual acuity in observation group was better than that in control group (Z=2.120, P=0.034). After operation, the incidence rate of complications in observation group was lower than that in control group (P<0.05). Compared with control group, the nursing satisfaction was higher in observation group (P<0.05). Conclusion Perioperative application of programmed nursing for patients with high myopia cataract can improve postoperative uncorrected visual acuity and reduce postoperative complications.