Objective To explore the value of transthoracic echocardiography (TTE) and CTA in the diagnosis of aortic dissection. Methods Collected 51 cases of aortic dissection confirmed by surgery in our hospital from May 2014 to May 2016 , preoperative are done cases of echocardiography and CTA examination were analyzed, and the evaluation of two methods of imaging in the diagnosis of aortic dissection. Results 51 cases patients, DeBakey typeⅠcases have 14, DeBakey typeⅡcases have 4, DeBakey type Ⅲ cases with 33. Echocardiography detection rate was 90.2% (46/51) of all cases, the CTA for all case detection rate was 96.1% (49/51), compare the differences between no statistical significance (P>0.05). Echocardiography in diagnosis of 5 cases, 1 case was DeBakey typeⅠ, 4 cases is DeBakey type Ⅲ. CTA in diagnosis of 2 cases were DeBakey type Ⅱ. Conclusion Transthoracic echocardiography and CTA inspection as two independent method has very important value to the diagnosis of aortic dissection, in the actual work will be a combination of both will improve the level of the diagnosis of aortic dissection and reference for clinical doctors to provide more accurate treatment.