Objective To retrospectively analyze the value of MRI in the diagnosis of 100 cases with pelvic cystic and solid space occupying lesions. Methods One hundred cases of female patients with pelvic occupying lesions who were treated in our hospital from October 2012 to December 2015 were analyzed retrospectively. All patients underwent MRI examination. The MRI findings of patients with different kinds of occupying lesions and the key points in the differential diagnosis of benign and malignant lesions were analyzed. Results Among the 100 patients, there were 65 cases with cystic occupying lesions, including 21 cases with ovarian cystadenoma, 14 cases with ovarian cystadenocarcinoma, 12 cases with ovarian endometriosis cysts, 10 cases with ovarian cysts, 8 cases with pelvic abscess. There were 35 cases with cystic and solid occupying lesions, including 20 cases with ovarian teratoma, 15 cases with ovarian cancer. Pelvic benign placeholder lesions were mainly cystic lesions with clear boundary, uniform signal, thin and uniform cystic wall, no enhancement; Malignant lesions were mainly cystic or solid mixed mass with irregular shape, wide range of involvement, cystic wall of uneven thickness, and visible wall nodule. The lesions showed mixed signal in T1WI and T2WI. The cystic wall and wall nodule had different degrees of reinforcement after enhanced scan. Conclusion The application of MRI in pelvic cystic and solid occupying lesions has such advantage as multi-axial imaging, high resolution of soft tissues etc.. Rich imaging sequences, dynamic enhanced scanning can be applied in differential diagnosis of cystic and solid lesions, and the differential diagnosis of benign and malignant lesions. It is of great application value on female patients with pelvic occupying lesions.