Objective To investigate the effects of coronary CT angiography on the drug therapy and the control of cardiovascular risk factors in patients with coronary heart disease. Methods 200 cases of patients with coronary heart disease (CHD) methods in January 2015 to 2016 January hospitalized in the cardiology department of our hospital, divided into < 70% stenosis group and is equal to or more than 70% stenosis group collected contrast the baseline data, and to all the selected patients were followed up, before and after contrast and between the two groups of cardiovascular related factors control, before and after the angiography accepted treatment. Results stenosis < 70% group, the total cholesterol (-0.4+1.1) mmol / L, triglyceride (-0.4+0.4 mmol / L, low density lipoprotein cholesterol (-0.3+0.6) mmol / L and high density lipoprotein cholesterol (+0.2 0.3 mmol / L, the degree of improvement, was significantly better than that of the stenosis is more than or equal to 70% group, the difference is statistically significant, P<0.05. The proportion of relatively lower than before after contrastenhanced CT coronary angiography in patients after total cholesterol (1.8+0.4) mmol / L, triglyceride (4.2 L.L) mmol / L, low density lipoprotein cholesterol (3.2+0.6) mmol / L and high density lipoprotein cholesterol (1.2+0.3 mmol / L significantly better than the corresponding index, and the difference was statistically significant, P<0.05. Coronary CT angiography in patients with systolic pressure (138.2+3. 8) mmHg, diastolic blood pressure (80.5+3.4) mmHg lower, and the difference was statistically significant, P<0.05. Coronary CT angiography in patients taking nitrates drugs, modulation drugs, antihypertensive drugs were 89.0%, 91.0% and 88.0%, compared with the previous significantly increased, the difference was statistically significant, P<0.05. Conclusion Coronary CT angiography results can increase the follow-up of patients with coronary heart disease medication compliance, and cardiovascular risk factors control has a positive impact, has important clinical value, it is worth promoting.