Objective To observe and analyze the different molecular subtypes of breast cancer patients with magnetic resonance (MRI) and molybdenum (CR), and to evaluate the effect of different molecular typing methods. Methods The correlation between the 80 breast cancer patients underwent enhanced MRI and mammography, analysis of patients with MRI and mammography imaging findings, and in the postoperative pathological inspection will determine the molecular typing, then analysis and MRI and the relationship between the molybdenum target molecules. Results The results showed that (1) Luminal-A and MRI in breast cancer: mammography showed multiple irregular mass like lesions, edge see burr and boundary fuzzy. A few lesions on mammography see microcalcification, P<0.05. (2) Luminal-B and MRI in breast cancer: mammography showed multiple irregular mass like lesions, MR found that most enhanced uneven enhancement and save edge burr, less lesion mammography see microcalcification, P<0.05. (3) triple negative breast cancer: MR enhancement, most of them showed ring enhancement and tumor see liquefied necrotic signal (P<0.05). (4) there is a strong link between the overexpression of HER2 type: molybdenum target on lesions of sand like calcification, enhanced MRI tumor to the surrounding strengthening (P<0.05). Conclusion combined application of MRI and mammography can identify different types of breast cancer, and imaging manifestations and different molecular typing and clinical observed in breast cancer patients with MRI and mammography performance through preliminary analysis with molecular typing, for clinical diagnosis and treatment of diseases.