Objective To evaluate the diagnostic value of magnetic resonance imaging in the diagnosis of breast diseases, and to investigate the clinical applicability of magnetic resonance imaging in the diagnosis of breast lesions, and to provide reference for further clinical application. Methods 95 patients with breast disease from January 2012 to 2015 March in Oncology department and Department of thoracic surgery of our hospital were collected and performed preoperative magnetic resonance imaging (MRI). The patients were suffered multi-item enhanced magnetic resonance imaging (MRI), to describe the morphological characteristics of lesion morphology edge, the determination of hemodynamic parameters obtained early lesions of the rate and the time signal intensity curve analysis, morphology, early and intensive rate and time signal intensity curve types of lesions. Results Malignant lesions were found in 43 cases, 43 lesions were found, accounting for 41.75%, 52 cases of benign lesions, 60 lesions were found, accounting for 58.25%. The malignant lesions showed irregular shape, and the peripheral tissue boundary was not clear in 35 cases, accounting for 81.40%; benign lesions showed round or oval, boundary light in 41 cases, accounting for 68.33%. The malignant lesions were not significantly higher than those in benign lesions, P<0.05. III in malignant lesions group was significantly higher than that in benign lesion group, and I was significantly lower than that in benign lesion group, P<0.05. The early enhancement rate of breast malignant lesions was 167.52 69.34%, the average early enhancement rate of benign lesions was 97.40 65.85%. The early enhancement rate of malignant lesions was significantly higher than that of benign lesions, P<0.05; less than 50% and 50-100% were significantly lower than those of benign lesions, P<0.05. Conclusion Application of dynamic enhanced magnetic resonance imaging in the diagnosis of breast lesions is still required to synthesize the lesion morphology, time signal intensity curve and early enhancement rate.