Objective To study the clinical features, treatment plan and CT imaging findings of 49 cases of patients with cerebral infarction. Methods 49 cases of patients with cerebral infarction who were admitted into the hospital during December 2014 to July 2015 were selected as the research objects. Patients who were older than or equal to 65 years old were treated as the elderly group (29 cases) while younger than 65 years old as the middle-aged group (20 cases). The clinical manifestations and CISS typing were compared between the two groups. Meanwhile, the intravenous thrombolytic therapy was implemented. With a month of follow-up, the efficacy of treatment plan was observed. Finally, through analyzing the results of head CT scan, the CT findings of patients with cerebral infarction were observed. Results In the elderly group, there were 10 cases of UE in CISS typing which were significantly higher than those in the middle-aged group (P<0.05). Most of the 49 patients were of LAA and UE type. In the elderly group, patients with hemiplegia, consciousness disorders and gatism were significantly more than those in the middle-aged group while patients with headaches in the middle-aged group were more than those in the elderly group. The comparison between groups was statistically significant (P＜0.05). The main clinical manifestations of the 49 patients were consciousness disorders, hemiplegia and headaches. After a month of thrombolytic therapy, the results were observed. Among the 49 patients, there was a case of death and a case in persistent vegetative state. There were 16 cases of 5 points of GOS, 22 cases of 4 points and 9 cases of 3 points. GOS were (3.24±0.59) points. Compared with those before the treatment, the difference was significant (P＜0.05). Among the 49 patients, there were 215 visible lesions scaned by CT, including 38 cases with lacunae brain infarction and 11 cases with multiple cerebral infarction. The distribution of lesions showed that there was cerebellar infarction in 15 cases, cortex infarction in 17 cases, brain stem infarction in 10 cases and basal ganglia infarction in 7 cases. Conclusion There is significant difference in the clinical characteristics of patients with different cerebral infarction. Most of the elderly patients are UE type and the incidence rates of hemiplegia and gatism in them are high. However, the middle aged patients manifest as headaches. The prognosis of patients who receive thrombolytic therapy for treating cerebral infarction is relatively good. CT diagnosis is beneficial to clinical disease evaluation, which can provide reliable basis for clinical treatment and the analysis of clinical characteristics.