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Head and Neck Imaging订阅

Magnetic Resonance Imaging Technology DTI in Alzheimer's Disease and the Application of Mild Cognitive Impairment

Author：GUO Long-jun1 , LI Kun-cheng 2 , CHEN Zhong-wei 3

affiliation：1 Department of Radiology,Beijing Rehabilitation Hospital Affiliated to the Capital University of Medical Sciences,Beijing 100144,China; 2 The Xuanwu Hospital Radiology Department to the Capital University of Medical Sciences,Beijing 100144.3 Beijing F

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Abstract

Objective to application of magnetic resonance diffusion tensor imaging (coursing together tensor imaging, DTI) research and identification of alzheimer's disease and mild cognitive impairment in patients with cerebral white matter damage. Methods for 45 cases of alzheimer's disease (AD) and 45 cases of patients with mild cognitive impairment (MCI) in brain DTI scan, measure the area of the opposite sex (FA) and an average score value dispersion rate (mean diffusivity, MD) and the comparison. Results compared with MCI group, AD groups on both sides of the parahippocampal gyrus, sides on both sides of the pillow, on both sides of the longitudinal beam and cingulate FA values were significantly lower after, P<0.05). Compared with MCI group, AD groups on both sides of the parahippocampal gyrus, sides on both sides of the pillow, on both sides of the longitudinal beam and the cingulate cortex, MD, of the rise, P<0.05). Conclusions DTI technology can be sensitive to detect the AD patients with MCI patients of cerebral white matter structure difference, which can be used for identification of MCI and AD.

【Keyword】Magnetic Resonance Diffusion Tensor Imaging; al Alzheimer's Disease; Mild Cognitive Impairment; Brain White Matter Lesions

【Chart number】R749.16 R445.2

【Document Identification Number】A

【DOI】 10.3969/j.issn.1672- 5131.2015.11.001

Chinese journal of CT and MRI

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