Head and Neck Imaging

Dynamic Observation of HIV Associated Dementia Brain Atrophy in MRI

Author:YUN Yong-xing, WANG Li-fei, LU Pu-xuan, et al.

affiliation: Department of Radiology, The Third People's Hospital of Shenzhen, Shenzhen 518112, Guangdong Province, China

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Abstract

Objective To explore the correlation between the development of brain atrophy and the progression of HAD by dynamic tracing of 16 patients with HAD. Methods The MRI data of 16 patients with HAD were analyzed retrospectively, and the correlation between dementia progression of HAD and brain atrophy was analyzed retrospectively from 1 to 9 months. Results A total of 16 cases of HAD with the development of brain atrophy, accompanied by the IHDS score decreased. The main manifestations of MRI were progressive brain atrophy and white matter lesions. The results showed that the frontal cortex became thinner, the volume of basal ganglia became smaller, and the expansion of the cerebral sulci and ventricles system. The results of statistical analysis showed that there was a negative correlation between brain atrophy and IHDS score (P<0.05). Conclusion The development of brain atrophy was negatively correlated with IHDS score. This study has positive significance for clinical diagnosis of HAD and prognosis.

【Keyword】Brain Atrophy; HIV Associated Dementia; Magnetic Resonance Imaging

【Chart number】R74;R75

【Document Identification Number】A

【DOI】10.3969/j.issn.1672- 5131.2017.08.002