Objective To investigate the effect of MRI enhanced scanning in the diagnosis of meningioma. Methods 82 cases of meningioma patients in our hospital were selected from March 2014 to December 2015. MRI scan and enhanced scan were performed in all patients. The position, size, shape, signal and enhancement of the lesion were observed. And combined with clinical data and surgical pathology results to make comprehensive analysis. Results 80 cases were confirmed by operation and pathological diagnosis were single lesions. The beside tumor located at the top of the cerebral convexity, parasagittal sinus, sphenoid ridge, falx cerebri, lateral ventricle, cerebellopontine angle patients were 33 cases, 17 cases, 9 cases, 14 cases, 2 cases, 5 cases. The tumor size between 1.3×1.0×1.2cm-6.3×4.8×6.2cm, tumor morphology were round or oval and half moon. The rate of MRI was 91.25% for all lesions. The difference was not statistically significant (P>0.05) compared with the results of surgery and pathology. The MRI signal of meningioma is characterized by a large signal on the T1WI and slightly high signal on T2WI. The minority in T1WI and T2WI showed mixed inhomogeneous signal. After enhancement scanning, most lesions showed marked enhancement, and a few showed that the enhancement was not uniform. Conclusion After the skull MRI scanning, especially MRI enhanced scan, the signal features and manifestations of meningiomas are characteristic. And the MRI enhanced scan of the skull has a high rate of coincidence rate, which has the function of localization and qualitative diagnosis. MRI enhanced scan can be used as an important imaging tool in the clinical diagnosis of meningioma. It is worthy of further promotion and application.