Objective To investigate the clinical value of MRI in the diagnosis of highgrade gliomas. Methods Retrospective analysis of MRI data of 87 patients with gliomas confirmed by surgery and pathology in our hospital from January 2013 to December 2015. And comprehensive analysis of the lesion location, morphology and other MRI imaging features. Results Among 87 patients, there are 56 cases diagnosed with astrocytoma, 15 cases of less sticks glioma, 9 cases with ependymoma room and 7 cases of medulloblastoma. According to the WHO classification criteria of glioma, classifying the gliomas on the basis of MRI imaging features, there are 9 cases of low-grade gliomas, including 3 cases of grade I, 6 cases of grade II, 78 cases of high-level brain gliomas, including 54 cases of grade III and 23 cases of grade IV patients. Conclusion In the diagnosis of glioma, MRI not only diagnose tumor location, size, shape, but also determine the tumor type and grade through a comprehensive analysis of MRI imaging and pathological features, which can effectively distinguish low-grade gliomas and high-grade gliomas. It has important clinical value, which is worthy of further promotion and application.