Head and Neck Imaging
Dual-source CT Hepatic Perfusion in Evaluating the Therapeutic Effect of TACE for HCC
Author:ZHU Bing-yin, GUO Shun-lin,YAO Yong-jie,et al.
affiliation:Department of Radiology, The First Hospital of Lanzhou University, Lanzhou 730000, Gansu Province, China
PDFAbstract
Objective Use perfusion parameters of dual-source CT to evaluate the effections of TACE thattreatsthe HCC. Methods 23 cases of the advanced HCCwhich confirmed by liver pathology ,erology and imaging without any treatment,that consists with Barcelona(BCLC)criteria for diagnosis of HCC, with the percontrast、postcontrast triple-phase of dual-source CT low dose scaningand the whole liver perfusion scaning performed 1-2 days before operation and a month after postoperation.Intravenous bolus injection of 50mL nonionic iodinated contrast agent(iopamidol 370mg/mL) at a 5mL/ s, then additional saline 50mLat a 5mL/s, to get 25 dynamic scans. The spcial perfusion softwarewas used to produce perfusion pseudo-color imaging, lastly, the following quantitative data of BV,TTS,ALP,PVP,HPI were used to assess the effect of preoperative and postoperative treatment with TACE. Results BV,ALP and HPI of the focus of iodine oil completely embolismare lower than preoperation,TTS and PVP are higher, the difference has statistical significance(P<0.05). TTS and PVP of the focus of iodine oil incompletely embolismare higherthan preoperation,ALP and HPI are lower,the difference has statistical significance(P<0.05). In the residual lesion area, compared with preoperation, ALP and HPI are higher, PVP is lower, the difference has statistical significance(P<0.05). The parameters in the focus of iodine oil incompletely embolism,compared with the residual lesion area, TTS and PVP are lower(P<0.05), ALP and HPI are clearly higher(P<0.01). Conclution CT perfusion imaging can be used to evaluate the effection of the TACE and monitor the postoperative residual lesions.
【Keyword】CT Perfusion Imaging; Hepatocellular Carcinoma; Transcatheter Arterial Chemoembolization
【Chart number】R735.7
【Document Identification Number】A
【DOI】 10.3969/j.issn.1672- 5131.2017.08.02480
Chinese journal of CT and MRI
th15Volume, th 8 Issue
2017Year08Month
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