Objective To explore the value of CTA in the diagnosis and treatment of gastrointestinal bleeding. Methods The clinical data of 60 patients with gastrointestinal hemorrhage were analyzed retrospectively, including preoperative and postoperative CTA examination and DSA data. The total time of interventional embolization, the time of exposure, the number of radiographs and the total radiation dose were recorded at the same time. There were 30 patients in the experimental group, who were examined by CTA before operation, and there were 30 patients in the control group who did not undergo CTA examination before the operation. CTA examination was performed 1 days after operation in the two groups, and the data above were analyzed statistically. Results The median age, the proportion of men and women and the median weight of the patients in the experimental group and the control group were basically the same, the difference was not statistically significant. The total time (65±12) min, the exposure time (218±22)s, the number of angiography (4±1) and the total radiation dose (468±35)mGy in the experimental group were significantly higher than those in the control group(81±15)min, (309±36)s,(6±2), (587±48)mGy (P <0.05). All cases underwent CTA after embolization, and gastrointestinal bleeding was found in 3 cases, followed by interventional embolization again, and CTA indicated bleeding stopped. No definite bleeding signs were found in all patients during the follow-up. Conclusion CTA examination before interventional embolization can evaluate the location of bleeding, the flow of bleeding and the shape of blood vessel, which have important guiding effect on the operation. It can shorten the total time of interventional embolization, the time of exposure, the number of radiography and the dose of radiation. The CTA examination after the interventional embolization can evaluate the curative effect and find the bleeding lesion in time, so it is worthy of clinical promotion.