Objective To investigate the clinical value of CT in the therapy of lobar pneumonia. Methods Retrospective analysis of CT data of 67 patients with lobar pneumonia in our hospital from January 2014 to January 2016. And comprehensive analysis of the CT imaging features. Results Among 67 patients, only 7 cases (10.4%) are double lung involved, 45 cases of right lung mostly involved, the right lung has 29 cases. There were 14 cases in the stage of exudation, 48 cases in the period of change, and 5 cases in dissipation period. The visible shadow with high density of 9 cases was significantly reduced within a week, shadow with high density of 52 patients was reduced to 70% after 2 weeks, the high density shadow of 56 patients disappeared after the 3 week, and high density shadow of 4 cases eliminated after 4 weeks. Conclusion The use of CT scanning can ascertain the lesion type of lobar pneumonia and determine the location and size of lesions, and utilize to the characteristics of CT scanning image to understand the stage of lobar pneumonia. It has significance clinical value in localization and qualitative of lobar pneumonia, displaying a very good role in guiding the condition treatment, which is worthy of further promotion and application.