Objective To analyze the imaging effects, complications and survival of CT guided radiofrequency ablation for lung cancer. Methods The related data of 76 patients with lung cancer treated by CT guided radiofrequency ablation in our hospital during May 2013 to May 2015 were retrospectively analyzed. The imaging changes were observed and compared before and after radiofrequency ablation, and the complications and 1-year survival rate were recorded. Results In 3 months, 6 months and 12 months of follow-up, the local control rates of lesions were 96.51%, 93.02%, and 86.05% respectively. 6 months after treatment, the tumor area and CT value [(13.26±3.14) cm2 , (50.60±17.18) HU] were significantly smaller and lower than those before treatment [(11.52±4.82) cm2 , (35.74±12.35) HU] (P<0.05). The incidence rates of pneumothorax, fever and bloody sputum were 13.16%, 17.10% and 6.58%. There were no serious surgical complications related to hemothorax, and the 1 year progression free survival rate was 73.68%. Conclusion CT guided radiofrequency ablation is effective, safe and feasible in the treatment of lung cancer, and the complications are few.