Objective To study the application of sufentanil combined spinal-epidural anesthesia in caesarean section and its effects on hemodynamics and incidence rates of postoperative traction pain and chills. Methods 276 puerperae who underwent cesarean section were randomly divided into observation group (ropivacaine+ sufentanil) and control group (ropivacaine) for combined spinal-epidural anesthesia. The anesthetic effects, hemodynamic indexes and occurrence of postoperative chills and traction pain were compared between the two groups. Results The excellent and good rates of anesthesia in the two groups were 97.10% and 94.93% respectively (P>0.05). At T2, the HR and MAP in the two groups were significantly changed compared with those at T0 (P<0.05). There were significant differences in the HR and MAP at T2 and T3 after anesthesia between the two groups (P<0.05). The incidence rates of adverse reactions in the two groups were 5.22% and 8.40% respectively (P>0.05), and the incidence rates of postoperative chills were 13.43% and 28.24% respectively (P<0.05), and the incidence rates of postoperative traction pain were 19.40% and 41.22% respectively (P<0.05). Conclusion Low-dose sufentanil in combined spinal-epidural anesthesia for caesarean section can improve the anesthesia quality, stabilize hemodynamic indexes, and reduce the occurrence of postoperative chills and traction pain, thus ensuring smooth operation and maternal-infant safety.