Objective To study PLT, PT, APTT, ALT, AST, BUN, Cr, UA changes in women with preeclampsia patients and its relationship with preeclampsia. Methods From January 2015 to December 2015 80 patients with preeclampsia who delivered in Chang Zhou Maternal and Child Health group, among which 38 cases were defined as early onset preeclampsia(EP)group and 42 cases were defined as late onset preeclampsia (LP) group. And 110 healthy women with same age and same stage of pregnancy were selected as the control group. Their blood pressure were normal and they had no obstetrical complications.Blood test and the major maternal-fetal complications were analyzed retrospectively. Results (1)There was significant difference on the the blood test of three groups of pregnancy women. There was significant difference on the UA test between LP and EP(P<0.05). (2)There was significant difference on the maternalfetal complications between LP and EP, which including hypertensive Heart Disease and eclampsia. Placental abruption and HELLP syndrome have no significant difference(P>0.05). (3) There was significant difference on the fetal complications between LP and EP, which including low birth weight infant , fetal distress and neonatal asphyxia. The rate of infant death have no significant difference between the two groups(P>0.05). Conclusion It is common that preeclampsia is complicated with blood test. Thus it is necessary to test PLT, PT, APTT, ALT, AST, BUN, Cr, UA in women with preeclampsia,UA is of the great significant importance. Early treatment can prevent maternal-fetal complications effectively