Objective To study and explore the application value of endoscopic resection in rectal polyps Endoscopic ultrasonography. Methods In our hospital from August 2015 June-2017 year period by colonoscopy in 90 cases with rectal polyps were found as the object of study, all patients underwent ultrasound endoscopy, endoscopic ultrasonography analysis results of rectal polyps and judge the rectal polyps nature, depth and vessels, according to a depth of ultrasound in rectal polyps Endoscopic resection or surgical resection for patients, the removed tissues were sent for pathological examination, the postoperative pathological diagnosis results as the gold standard, calculation of EUS diagnosis sensitivity, on the nature of the rectal polyp specificity, accuracy, positive predictive value, negative predictive value, and calculation of endoscopic ultrasonography for rectal polyps malignant lesions T staging diagnosis coincidence rate, analysis of endoscopic ultrasonography for straight intestinal polyp pedicle The diagnosis distribution of blood vessels and surrounding mucosa. Results The diagnostic sensitivity of endoscopic ultrasonography for rectal polyps nature of the specificity, accuracy, positive predictive value, negative predictive value were 97.50%, 100%, 97.78%, 100%, 83.33%, the consistency between the results of the diagnosis and postoperative pathological diagnosis results. Endoscopic ultrasonography for rectal polyps malignant lesions staging (stage T1a, T T1b, T2, total) rate was 83.33%, with 75%, 83.33%, 100% diagnosis, the diagnosis of vascular distribution of rectal polyp pedicle and surrounding mucosa under coincidence rate was 96.61%, 95.74%. Conclusion Endoscopic resection of rectal polyps Endoscopic ultrasonography can be on the nature, depth of invasion of rectal polyps. The distribution of vessels were clear, the high diagnostic accuracy, conducive to the development of scientific and reasonable treatment for patients, in order to improve the prognosis.