Objective To investigate the value of procalcitonin on anti-infections treatment in aged cardiac failure combined with pneumonia. Methods 84 cases of aged cardiac failure combined with pneumonia in our hospital from March 2016 to March 2017 were selected and divided into control group (42 cases) and observation group (42 cases) according to random number table. Control group was given anti-infections treatment based on clinical symptoms and illness condition, observation group was given procalcitonin on basis of control group. Results After corresponding treatment, ESR, CRP level of observation group were all lower than control group (P<0.05). Anti-infections course, hospitalization costs, antibacterial agents costs of observation group were all lower than control group (P<0.05). The difference of hospital stays between the two groups had no statistic significance (P>0.05). Conclusion Procalcitonin has significant effect on anti-infections treatment in aged cardiac failure combined with pneumonia and is suitable for clinic promotion