Objective To explore the clinical value of mini-laparoscopic high ligation on inguinal hernia in children. Methods 70 children with inguinal hernia treated in hospital from Sep. 2016 to Oct. 2017 were randomly divided into study group (35 cases) and control group (35 cases). The control group was treated with conventional operation, while the study group was treated with mini-laparoscopic high ligation of hernial sac. The intraoperative and postoperative general situations in the two groups were observed, the pain conditions in the two groups were evaluated (pain time, pain intensity 6h after operation [Children’s Hospital EasternOntario Pain Scale,(CHEOPS)]), and the incidence rates of complications and recurrence rates 6 months after operation in the two groups were recorded. Results The operation time, incision length, blood loss, hospitalization time and postoperative bed time in the study group were all less than those in the control group (P<0.05), the pain time and CHEOPS score 6h after operation in the study group were all less than those in the control group (P<0.05), the postoperative fever rate and recurrence rate 6 months after operation in the study group were all lower than those in the control group (P<0.05), there was no significant difference in hydrocele and incidence of scrotum / labium majus swelling between the two groups (P>0.05). Conclusion Minilaparoscopic high ligation which has considerable value, can not only significantly improve the intraoperative and postoperative general situation and pain condition of children with inguinal hernia, but also reduce the postoperative fever and recurrence rates while providing treatment experience for children.