Head and Neck Imaging
The Study on Plasma Lipids and Inflammation in Active Inflammatory Bowel Diseases
Author：LU Yong-wen, YAO Fan-bao, HUANG Shi-yao, et al
affiliation：Department of Gastroenterology, The People’s Hospital of Sanshui, Foshan 528100, Guangdong Province, China
PDFAbstract
Objective To evaluate the relationships between infammatory parameters, plasma lipids and phospholipid fatty acid (FA) composition in patients with active UC and CD. Methods Diet, the Harvey-Bradshaw Activity Index (HBAI), inammatory parameters, lipoproteins and FA composition were assessed in 28 UC and 30 CD. Results No differences in clinical parameters were observed in the two groups. Total cholesterol correlated inversely with the number of bowel movements in both groups. Total and HDL cholesterol were inversely related to C-reactive protein (CRP) in CD while HDL correlated with CRP in UC. CRP and IL-6 were related to Saturated FA in the both group, in addition, CRP correlated positive with n-6 MUPFand HDL but inversely with n-3 MUPF. Conclusion Lipoproteins and FA composition were varied in active inflammatory bowel diseases and were correlated with the systemic inflammatory status, but was unrelated to dietary intake and intestinal disease activity.
【Keyword】Ulcerative Colitis(UC); Crohn’s Disease(CD); Activity; Plasma Lipids; Infammatory Parameters
【Chart number】R574
【Document Identification Number】A
【DOI】10.3969/j.issn.1009-3257.2018.03.021
Journal of Rare Diseases
th25Volume， th 3 Issue
2019Year11Month
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