Head and Neck Imaging
Curative Effect of Glucocorticoid Combined With N-Acetyl-L-cysteine, Macrolides on COPD with ILD
Author：LIU Shu-xiang. YANG Xiu-zhi.
affiliation：Department of Respiratory Medicine, Central Hospital of Kaifeng City, Kaifeng 475000, Henan Province, China
PDFAbstract
Objective To investigate the curative effect and safety of glucocorticoid combined with N-Acetyl-L-cysteine, macrolides on COPD with ILD. Methods 59 cases of COPD with ILD in our hospital from March 2014 to March 2017 were selected and divided randomly into control group (27 cases) and observation group (32 cases), control group was given conventional oxygen cure, glucocorticoid, cough phlegm, anti-inflammatory, observation group was given N-Acetyl-L-cysteine, azithromycin on this basis, clinic effect, adverse reactions of the two groups were compared. Results Total efficiency of observation group (93.75%) was significantly higher than control group (74.07%) (P<0.05). Total adverse reaction rate of observation group (15.63%) was lower than control group (25.93%) (P>0.05). Conclusion Glucocorticoid combined with N-Acetyl-L-cysteine, macrolides has significantly effect on COPD with ILD, adverse reactions will not increase and the safety is higher.
【Keyword】COPD; ILD; Glucocorticoid; N-Acetyl-L-cysteine; Azithromycin; Safety
【Chart number】R562;R563
【Document Identification Number】A
【DOI】10.3969/j.issn.1009-3257.2018.03.007
Journal of Rare Diseases
th25Volume， th 3 Issue
2019Year11Month
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