The Changes of Serum TIMP-1, IL-10, hs-CRP and TH in School-age Children with Asthma Before and After Treatment

Author:XIE Ze-zhou

affiliation:ZhuPu Hospital of Haojiang District, Shantou 515071, Guangdong Province, China

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Abstract

Objective To investigate the changes of serum TIMP-1, IL-10, hs-CRP and TH in school-age children with asthma before and after treatment. Methods 126 children with asthma were collected, compared with 55 cases of healthy children. The level of serum TIMP-1, IL-10, hs-CRP and TH were compared respectively. Results Serum levels of TIMP-1, IL-10, hs-CRP and TH were significantly different before and after treatment and both had significant abnormalities than the control group in the asthma group(P<0.05). Serum levels of TIMP-1, IL-10, hs-CRP were significantly higher in attack than remission(P<0.05). Conclusion Combined detection of serum TIMP-1, IL-10, hsCRP and TH levels, contribute to the diagnosis of asthma and identification of different stages of this disease.

【Keyword】Asthma; TIMP-1; IL-10; hs-CRP; Thyroid Hormone

【Chart number】R725.6

【Document Identification Number】A

【DOI】10.3969/j.issn.1009-3257.2016.05.010