Objective To explore the psychological, physiological and social support and other factors on the production of natural childbirth process. Methods From January 2015 to January 2016, 600 for natural childbirth maternal natural childbirth in our hospital were selected as the research object, all women were randomly divided into intervention group (n=300) and control group (n=300), the intervention group was given psychological, physiological and social support and other factors were given routine nursing intervention, patients in the conventional group, the natural childbirth labor situation were compared between the two groups. Results The intervention group mothers levelⅠ incidence of pain was significantly higher compared with the conventional, P <0.05. Maternal pain intervention group grade Ⅱ, grade Ⅲ pain incidence was significantly lower compared with the conventional group, P<0.05. Postpartum hemorrhage intervention group was significantly less compared to the conventional, P<0.05. Conclusion Psychological, physiological and social support intervention factors improve the maternal labor status, reduce maternal pain, postpartum hemorrhage and cesarean section rate, and can be used in natural childbirth.