The Preemptive Analgesic Efficacy of Flurbiprofen Axetil: A meta-analysis
Author：WANG Ke, ZHENG Li-min, LUO Tao
affiliation：Anhui medical university, Hefei 230032, Anhui Province, China
PDFAbstract
Objective To evaluate the effectiveness of preoperative administration with Flurbiprofen Axetil for postoperative pain relief. Methods Databases such as PubMed, WANFANG,CNKI were searched to identify randomized controlled trials (RCTs) involved in Flurbiprofen Axetil for preemptive analgesia from 2000 to 2016. The quality of studies were selected and evaluated, and Visual analogue score (VAS) at 6h, 12h, 24h after surgery were calculated by Review manager 5.3 software. Results A total of 16 RCT studies involving 804 patients were included in this study. The results of this Meta-analysis showed that: 6h-VAS[SMD:-0.50,95%CI(-0.84,-0.17),P=0.003],12h-VAS[SMD:-0.70,95%CI(- 1.16,-0.25),P=0.002], 24h-VAS[SMD:-0.15,95%CI(-0.27,-0.04),P=0.008]. Conclusion The present data shows that preoprative Flurbiprofen axetil administration is efficacy for reducing acute postoperative pain.
【Keyword】Flurbiprofen Axetil; Preemptive Analgesia; Meta-analysis
【Chart number】R971+.1
【Document Identification Number】A
【DOI】10.3969/j.issn.1009-3257.2016.06.024
Journal of Rare Diseases
th23Volume， th 2 Issue
2019Year11Month
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