The Value of 3D-ASL in the Preoperative Grading of Gliomas
Author：ZHAO Jun-xiong, LIANG Li-hua, TAN Zhi
affiliation：Guangdong Medical University, Zhanjiang 524023, Guangdong Province, China
PDFAbstract
Objective To discuss the value application of 3D-ASL in the preoperative grading of gliomas. Methods Collect 18 cases of patients with glioma proved by pathology after surgery, including 8 cases of low grade (Ⅰ-Ⅱ grade) and 10 cases of high grade (Ⅲ-Ⅳ grade). Each patient were scaned on routine head MRI, enhanced scan, 3D-ASL before operation and reconstruct cerebral blood flow diagram (CBF) figure. According to the enhanced scanning we should avoid the areas of necrosis sac and vascular of the tumor and focus ROI on the material composition, which coverd 20-30mm2. Measuring the solid part of CBF and the mirror region of CBF in each case and make the ratio , tumor CBF/ image CBF to work out the rCBF. Then compared the two samples with t test in order to distinguish the difference between rCBF in the high and low grading of gliomas. Results The value of rCBF is (2.65±0.82) in high grade gliomas was higher than the value of rCBF (1.64±0.63) in low grade gliomas. The difference between the two groups was statistical significantly (t=4.32,P<0.01). Conclusion 3D-ASL has high accuracy in the preoperative grading of gliomas, which is helpful for guiding clinical treatment.
【Keyword】3D-arterial Spin Labeling; Glioma
【Chart number】R739.4
【Document Identification Number】A
【DOI】10.3969/j.issn.1009-3257.2016.06.004
Journal of Rare Diseases
th23Volume， th 2 Issue
2019Year11Month
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