Effect of Immunmmodulatory Strategy on Acute Exacerbation of Chronic Obstructive Pulmonary Disease*
Author：LONG Xiang, ZENG Chao, MO Jian-ming,et al.
affiliation：Department of Respiratory Disease, Peking University Shenzhen Hospital, Shenzhen 518000, Guangdong Province, China
PDFAbstract
Objective To study the effect of thymosin α1 and Ulinastatin in the treatment of acute exacerbation of chronic obstructive pulmonary disease (AECOPD). Metheds 68 AECOPD patients were randomized divided into control group and treatment group. Control group received conventional treatment. Patients in the treatment group were treated with conventional treatment puls thymosin α1 and Ulinastatin. Results In treatment group PaO2, FEV1 volum were increased than control group (P<0.05). Serum TNF-α and IL-8 level intreatment group were decreased significantly than control group (P<0.05). Conclution Thymosin α1 and Ulinastatin treatment enhances AECOPD curative effect.
【Keyword】 Acute Exacerbation of Chronic Obstructive Pulmonary Disease; Ulinastatin; Thymosin α1; Immunmmodulatory
【Chart number】R563
【Document Identification Number】A
【DOI】10.3969/j.issn.1009-3257.2016.06.006
Journal of Rare Diseases
th23Volume， th 2 Issue
2019Year11Month
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