目的 探究姑息护理对晚期胰腺癌患者癌因性疲乏及负性情绪的影响。方法 选取2015年12月-2017年12月我院收治 的102例晚期胰腺癌患者为研究对象，按抽签法平均分为试验组与对照组，每组各51例。对照组给予常规护理，试 验组在对照组基础上采取姑息护理措施。分别于护理干预前、护理干预1个月后采用PIPER-疲乏量表(PFS)、汉密尔 顿焦虑评价量表(HAMA)与汉密尔顿焦虑抑郁评价量表(HAMD)评估患者主观疲劳不适感及负性情绪。结果 护理干预1 个月后，试验组中重度疲乏率、HAMA和HAMD得分均较干预前明显降低，且低于于同期对照组(P均＜0.05)；对照组 护理干预前后中重度疲乏率、HAMA和HAMD得分变化均不明显(P均＞0.05)。结论 姑息护理有助于改善晚期胰腺癌患 者的癌因性疲乏及负性情绪。

Objective To explore the effects of palliative care on cancer-related fatigue and negative emotions in patients with advanced pancreatic cancer. Methods A total of 102 patients with advanced pancreatic cancer admitted to our hospital from December 2015 to December 2017 were selected for the study and were divided into experimental group and control group according to the lottery method, with 51 cases in each group. Control group was given routine care, and experimental group was given palliative care measure on the basis of control group. The subjective fatigue discomfort and negative emotions were evaluated by PIPER-Fatigue Scale (PFS), Hamilton Anxiety Scale (HAMA) and Hamilton Depression Scale (HAMD) before nursing intervention and after 1 month of nursing intervention. Results After 1 month of nursing intervention, the moderate-severe fatigue rate and scores of HAMA and HAMD in experimental group were significantly lower than those before intervention, and were lower than those in control group at the same time period (all P<0.05). There were no significant changes in the moderate-severe fatigue rate and scores of HAMA and HAMD in control group before and after nursing intervention (all P>0.05). Conclusion Palliative care can improve the cancer-related fatigue and negative emotions in patients with advanced pancreatic cancer.