目的 探讨血小板抗体与血小板输注效果的关系及其意义。方法 收集我院2013年9月-2015年9月收治的淋巴瘤患者 50例，统计所有患者的输血次数，检测患者输血前后的血小板抗体，分析患者血小板抗体与输血次数和输血效果的 关系，此外，将50例患者随机分为对照组25例，实验组25例，分别输注随机血小板和配型血小板，比较两组的输血 效果。结果 随着输血次数的增加，患者的血小板抗体阳性率也随之升高(P<0.05)；血小板抗体阳性患者的输注无 效率(60.87%)显著高于血小板抗体阴性患者的输注无效率(29.63%)(P<0.05)；试验组血小板输注有效率(40.0%)明 显高于对照组血小板输注有效率(72.0%)。结论 输血次数的增加可以增加血小板抗体的产生，患者在输注血小板之 前加强血小板抗体检测和血小板配型可以提高血小板输注有效率。

Objective To explore the effects and significance on platelet antibody detection and platelet transfusion effect of patients with lymphoma. Methods 50 patients from September 2013 to September 2015 with lymphoma in our hospital were selected as research subjects. Firstly, patient′ times of transfusion were counted and their platelet antibody was tested before and after the transfusion, then observe the relation between the positive rate of platelet antibody and times of transfusion, afterwards, the patients received platelet transfusion and the test result of platelet antibody and its relation with the effect of platelet transfusion were evaluated; at last, the 50 patients were randomly allocated to test group and control group, with 25 patients in each group. Patients in the control group received random platelet transfusion and patients in the test group received matched platelet transfusion. The effect of platelet transfusion between the two groups was evaluated. Results 23 cases(46.0%)of 70 patients had positive test result of platelet antibody. With the times of transfusion increasing, the positive rate of platelet antibody gradually increases(P<0.05). The PTR in positive platelet antibody was 60.87%,the PTR in negative platelet antibody was 29.63%,with statistical difference (P<0.05).The effective rate of platelet transfusion in control group was 40.0%,and that in test group was 72.0%,with statistical difference(P<0.05). Conclusion More of the times of blood transfusion will increase more platelet antibody, platelet antibody detection and matched platelet transfusion of patients with lymphoma. have great significance for improving the effects of platelet transfusion.