摘要
目的 探讨CT双能量技术碘图在肺良恶性病变鉴别中的临床价值。方法 39例肺部结节或肿块患者(良性11例,恶性 28例)均经病理证实行胸部CT双能量模式平扫及双期增强扫描。将双期双能量增强数据调入Dual-energy软件,选择 “Lung Nodules”应用得到碘图。通过测量并计算得出病灶动脉期(AP)、静脉期(VP)及动静脉期间(AV)碘图CT值。 采用独立样本t检验比较良恶性病变之间碘图CT值的差异。结果 良、恶性病变之间碘图(AP)、碘图(VP)CT值均无统 计学意义(t=﹣0.61,P>0.05;t=1.50,P>0.05),而碘图(AV)CT值净增值有统计学意义(t=2.97,P<0.05)。结论 CT 双能量扫描碘图为肺内良恶性病变的鉴别提供了新的诊断方法,在临床中具有一定的应用价值。
Objective To explore the application value of Dual-energy CT iodine image in differentiating benign and malignant pulmonary lesions. Methods All 39 cases with pulmonary nodules or tumors (benign 11 cases, malignant 28 cases) were confirmed by pathology. Chest CT with dual-energy mode plain scan and double-phase enhanced scans were performed. The double-phase enhanced images were sent to the Dual-energy software, select the application of the "Lung Nodules" to acquire the iodine-image. The iodine-image CT values of lesions arterial phase (AP), venous phase (VP) and arteriovenous period (AV) were obtained by measurement and calculation. The differences of iodineimage CT value between benign and malignant lesions was compared by independent sample t test. Results There were no statistically differences among iodine-image CT value in both arterial and venous phase between benign and malignant lesions(t=﹣0.61, P>0.05; t=1.50, P>0.05). However statistically significant differences of iodine-image CT value in arterial-venous phase were seen between benign and malignant lesions (t=2.97, P<0.05). Conculusion Dual energy scanning iodine image provides a new diagnostic method in differentiating benign and malignant lesions, and has good application value in clinical.
【关键词】双能量技术;碘图;肺内病变
【中图分类号】R563
【文献标识码】A
【DOI】10.3969/j.issn.1009-3257.2018.05.012
前言
肺癌是全世界发病率和死亡率最高的恶性肿瘤之 一,约占所有肿瘤的12.4%[1],且呈逐渐增长趋势, 严重威胁着人类的健康及生命,因此早期诊断,患者 能够及时手术治疗,存活率明显提高。虽然影像学技 术发展迅速,但胸部CT扫描仍是临床上最为常规及有 效的检查方法,一般情况下CT主要依靠肺结节或肿块 的形态学特征(如分叶、毛刺、胸膜凹陷征等)及病灶 的强化方式来鉴别其良恶性,但部分肺良性病变在形 态学上及强化表现上与部分恶性肿瘤相似,诊断比较 困难,所以常规CT在诊断上具有一定局限性[2-3]。目 前双源CT(Dual-source CT)通过特有的双能量技术,能够实现碘与软组织的分离,获得碘图,能更准确反 映组织强化水平。本文主要探讨CT双能量扫描中碘图 在肺内良恶性病变鉴别中的临床应用价值。
罕少疾病杂志
第25卷, 第 5 期
2019年11月
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