摘要
目的 分析舒芬太尼复合罗哌卡因用于剖宫产术后硬膜外自控镇痛的效果。方法 将2013年9月-2016年2月在我院行 剖宫产术且术后采用硬膜外自控镇痛产妇纳入研究范围,将两组患者临床资料进行对比分析,筛选采用罗哌卡因镇 痛的130例产妇作为对照组,并按1:1比例选取通气采用舒芬太尼复合罗哌卡因镇痛的130例产妇作为观察组,将两 组镇痛效果进行对比分析。结果 经查阅分析发现,采用舒芬太尼复合罗哌卡因硬膜外自控镇痛的观察组产妇,VAS 评分为0-3分及4-6分产妇比例均显著大于对照组,其总有效率为88.46%,较对照组的77.69%高;且不同时间节点 时,观察组产妇静止、翻身时VAS评分均显著低于对照组,以上对比差异均具统计学意义(P<0.05);但术后镇痛 期间,观察组产妇出现恶心呕吐2例,低血压3例,下肢麻木5例,皮肤瘙痒2例,头晕3例,总发生率为10.77%,与 对照组的11.14%对比无差异,不具统计学意义(P>0.05)。结论 舒芬太尼镇痛效果优越,与罗哌卡因复合使用不 仅安全性佳,还具协同镇痛机制,能显著减轻剖宫产术后疼痛。
Objective To analyze the effects of sufentanil combined with ropivacaine on patient-controlled epidural analgesia after cesarean section. Methods Maternal performed the cesarean section and postoperative patient-controlled epidural analgesia in our hospital from September 2013 to February 2016 were included in the study. The clinical data of the two groups were compared and analyzed. 130 cases of maternal with ropivacaine analgesia were selected as the control group, and another 130 cases of maternal with sufentanil combined with ropivacaine by1: 1 ratio were selected as the observation group, and analgesic effects were compared and analyzed between the two groups. Results After checking and analyzing, the proportion of VAS score of 0-3 and 4-6 points in the observation group using sufentanil combined with ropivacaine epidural analgesia were significant higher than that in the control group, and the total effective rate was 88.46%, which was higher than that in the control group with 77.69%. At different time points, the VAS scores of the observation group were significantly lower than those of the control group when they were resting and turning over, and the difference between the two groups was statistically significant (P<0.05). However, during the postoperative analgesia, there were 2 cases of nausea and vomiting, 3 cases of low blood pressure, 5 cases of lower limb numbness, 2 cases of skin itching and 3 cases of dizziness in the observation group. And the total incidence rate was 10.77% in the observation group and 11.14% in the control group, therefore the difference was not statistically significant (P>0.05). Conclusion Sufentanil can have superior analgesic effect, and the combination with ropivacaine can not only have good safety, but also have a synergistic analgesic mechanism to significantly reduce the pain after cesarean section.
【关键词】舒芬太尼;罗哌卡因;硬膜外自控镇痛
【中图分类号】R719;R45
【文献标识码】A
【DOI】10.3969/j.issn.1009-3257.2018.02.016
前言
剖宫产术作为有创手术,对机体的创伤显而易 见,产妇因手术应激、心理因素等常导致极易疼痛阀 值降低,对疼痛敏感度上升,不仅不利于术后恢复, 还影响母乳分泌,不利于母婴健康[1]。我院将舒芬太 尼复合罗哌卡因作为剖宫产术后硬膜外自控镇痛,并 取得较满意镇痛效果,因当今对舒芬太尼镇痛导致的不良反应尚存争议,故笔者将我院采用舒芬太尼复合 罗哌卡因进行术后硬膜外自控镇痛的产妇临床资料进 行对比分析,旨在为舒芬太尼的使用提供有价值的临 床数据,现作如下报道。
罕少疾病杂志
第25卷, 第 2 期
2019年11月
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