目的 对首发精神分裂症、双相障碍、抑郁障碍认知功能进行分析探讨。方法 选取我院2014年10月-2016年10月收 治的首发精神分裂症患者60例、双相障碍患者55例[分为躁狂亚组（35例）和抑郁亚组（20例）]、抑郁障碍患者40 例，另选取60例正常人作为对照组，采用RBANS（神经心理测查系统）评估认知功能。结果 首发精神分裂症组、双 相障碍组RNANS总分明显低于对照组RNANS总分，首发精神分裂症、双相障碍以及抑郁障碍患者即刻记忆因子得分明 显低于对照组患者即刻记忆因子得分，首发精神分裂症、双相障碍、抑郁障碍组言语功能因子得分明显低于对照组 患者言语功能因子得分，双障碍组言语功能因子得分明显低于首发精神分裂症组言语功能因子得分，首发精神分裂 症组注意因子得分明显低于抑郁障碍组和对照组注意因子得分，首发精神分裂症、双障碍、抑郁障碍患者延迟记忆 因子得分明显低于对照组患者延迟记忆因子得分，差异有统计学意义（P<0.05）。结论 首发精神分裂症、双相障 碍、抑郁障碍的患者认知功能均存在不同程度的损伤，首发精神分裂症轻于双相障碍，重于抑郁障碍。

Objective To analyze the cognitive function of first episode schizophrenia, bipolar disorder and depressive disorder. Methods 60 cases of patients with first episode schizophrenia, 55 patients with bipolar disorder were divided into manic subgroup (35 cases) and depression subgroup (20 cases), 40 patients with depressive disorder, which were selected in our hospital from October 2014 to October 2016, 60 normal subjects were selected as the control group. RBANS (neuropsychological test system) was used to evaluate the cognitive function. Results The total scores of RNANS in the first episode schizophrenia group and bipolar disorder group were significantly lower than those in the control group (P<0.05). The scores of immediate memory factor in patients with schizophrenia, bipolar disorder and depressive disorder were significantly lower than those in the control group , The scores of speech function factors in the first episode schizophrenia, bipolar disorder and depression group were significantly lower than those in the control group, and the score of speech function factor in the double obstruction group was significantly lower than that in the first episode schizophrenia group. The score of attention factor in schizophrenia group was significantly lower than that in depressive disorder group and control group. The score of delayed memory factor in patients with first episode schizophrenia, double obstruction and depressive disorder was significantly lower than that in control group, the difference was statistically significant (P<0.05). Conclusion The first generation of schizophrenia, bipolar disorder, depression, cognitive function in patients with varying degrees of injury, first episode schizophrenia is lighter than bipolar disorder, more severe than depression.