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·腹部疾病·

6例子宫血管平滑肌瘤病的临床分析

作者:王文翔1 高玉霞1 张付美2 陈彩霞1

所属单位:1.河南省新乡市中心医院妇科妇瘤一科 2.河南省新乡市中心医院病理科 (河南 新乡 453000)

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摘要

目的 探讨子宫血管平滑肌瘤病的临床诊治。方法 回顾性分析6例子宫血管平滑肌瘤的临床病理资料。结果 患者平 均年龄40.1岁;平均孕产次分别为3,1.7;33.3%患者有子宫相关手术史。临床表现主要为盆腔包块(4/6),月经改 变(2/6),无1例术前确诊,均以“子宫肌瘤”收治。术中瘤体呈白色条索状分布,沿子宫血管方向生长,6例均为 术后诊断。40岁以上病变弥漫者行全子宫切除及盆腔肿瘤切除,病灶局限于宫体的年轻患者行病灶切除。随访时间 1-25月,1例复发(首次手术时未全部切除肿瘤)。结论 子宫血管平滑肌瘤育龄期女性多见,临床表现无特异性,确 诊依靠病理组织检查,手术宜彻底切除肿瘤累及区域,术后应严密随访。

Objective To explore the clinical characteristics, pathology and treatment of uterus intravenous leiomyomatosis. Methods A total of 6 cases of intravenous leiomyomatosis which confirmed by pathologically were analyzed retrospectively. Results The mean age of 6 patients was 40.1, average times of pregnant and labor were 3 and 1.7. 33.3% patients had a history of uterine-related surgery. Most common symptoms were pelvic mass and abnormal uterine bleeding. None of them was diagnosed preoperative. The pathological manifestation was smooth muscle cell grow along the blood vessels. All patients were diagnosed by postoperative pathology. Over 40 years old patients with diffuse lesions were performed hysterectomy and pelvic tumor resection. Young patients with lesions confirmed to uterus were performed leimyoma resection. The follow-up time was 1-25 months, one patient relapsed (not completely resection). Conclusion Intravenous leiomyomatosis had no specific symptoms, and it mostly affects the women with childbearing age. Pahtology is most valuable for the diagnosis. Radically resection is the main treatment for intravenous leiomyomatosis. All patients need routine follow-up after the operation.

【关键词】血管平滑肌瘤;子宫

【中图分类号】R73;R81

【文献标识码】A

【DOI】10.3969/j.issn.1009-3257.2017.04.020

前言

血管平滑肌瘤病(intravenous leiomyomatosis, IVL)是血管环形平滑肌束组成的良性肿瘤,起源自平 滑肌细胞,早期生长在血管内,局限在子宫,病变可 进展累及至盆腔血管,延伸至下腔静脉,右心房,甚 至引发肺动脉栓塞。因病变弥漫手术困难,且术前难 以确诊,故提高对本病的认识十分重要。现对我院 2013年10月至2016年11月收治的6例血管平滑肌瘤病 患者的临床资料总结分析,探讨本病的病理特征及临 床诊治。