目的 比较不同糊剂结合牙胶尖在根管治疗一次法充填中的疗效及并发症。方法 选择2014年4月-2016年9月在我 院接受根管治疗一次法填充的患者136例共159颗患牙，随机法分为甲组、乙组和丙组，每组患牙53颗，分别用 Cortisomol糊剂、Vitapex糊剂、氧化锌丁香油糊剂加牙胶尖进行根管一次法填充治疗。比较三组患者术后1周疼 痛程度并随访1年后治疗疗效。结果 甲组、乙组无疼痛和轻度疼痛者与丙组比较显著较多，差异有统计学意义 （P<0.05）；甲组中度疼痛者与丙组比较显著较少，差异有统计学意义（P<0.05）；甲组、乙组总有效率98.1%、 96.2%与丙组84.9%比较明显较高，差异有统计学意义（P<0.05）；随访甲组自发性疼痛3例与丙组11例比较，差异 有统计学意义（P<0.05）。结论 Cortisomol糊剂、Vitapex糊剂、氧化锌丁香油糊剂加牙胶尖在根管治疗一次法中 均具有较好的效果，其中Cortisomol糊剂加牙胶尖对患者疼痛症状缓解效果更好，远期疗效也更好。

Objective To compare the curative effects and complications of different pastes combined with gutta percha point in one-time filling root canal treatment. Methods From Apr. 2014 to Sep. 2016, a total of 136 patients (159 affected teeth) who accepted one-time filling root canal treatment in our hospital were taken as the clinical research objects. All the affected teeth were randomly divided into A group (53 cases) , B group (53 cases) and C group (53 cases), and treated by one-time root canal filling with gutta percha point plus cortisomol paste (group A), vitapex paste (group B) and zinc oxide eugenol paste (group C). The pain degrees 1 week after operation and 1 year follow-up curative effects in the three groups were compared. Results Patients with no or mild pain in A and B group were obviously more than those in C group, and their differences were statistically significant(P<0.05), patients with moderate pain in A group were obviously less than those in C group, and their difference was statistically significant(P<0.05), the total effective rates in A and B groups were respectively 98.1% and 96.2% which were remarkably higher than that in C group 84.9%, and their differences were statistically significant(P<0.05). After 1 year follow-up, there were 3 cases of spontaneous pain in A group and 11 cases of spontaneous pain in C group, and the difference between the two groups was statistically significant(P<0.05). Conclusion Gutta percha point plus cortisomol paste, vitapex paste and zinc oxide eugenol paste in one-time filling root canal treatment all have good effects, espically cortisomol paste plus gutta percha whose pain relief effect and long-term effect is better.