摘要
目的 研究和分析CPAP呼吸机联合氨溴索治疗新生儿呼吸窘迫综合症的临床观察。方法 选取2014年2月-2016年2月 来本科室就诊的100例新生儿呼吸窘迫综合征患儿,按照治疗顺序将其分成两组,一组是采用常规机械通气联合氨 溴索治疗的对照组,一组是采用CPAP呼吸机联合氨溴索治疗的观察组,每组50例,观察两组患儿的治疗有效率、 治疗前后血气指标等。结果 观察组患儿的治疗有效率为98%(49/50),对照组患儿的治疗有效率为84%(42/50),两 组患儿治疗有效率差异明显(χ2 =7.111,P=0.007);观察组患儿血气指标恢复明显优于对照组患者,经过24h、48h 后,观察组与对照组患儿PaO2升高明显、PaCO2降低显著、FiO2下降、OI降低,与治疗前相比,差异显著。结论 新 生儿呼吸窘迫综合症应用CPAP呼吸机联合氨溴索治疗,效果明显,治疗有效高、血气指标恢复较好,具有极高的推 广价值,应大力推广。
Objective To study and analyze the clinical effect of CPAP ventilator combined with ambroxol in neonatal respiratory distress syndrome. Methods One hundred newborns with respiratory distress syndrome were selected from February 2014 to February 2016. The patients were divided into two groups according to the order of treatment. One group was treated with conventional mechanical ventilation combined with ambroxol Control group, one group was treated with CPAP ventilator combined with ambroxol observation group, each group of 50 cases, the observation of two groups of children in the treatment of effective blood gas before and after treatment indicators. Results The effective rate of treatment was 98% (49/50) in the observation group and 84% (42/50) in the control group. There was significant difference between the two groups (χ2 =7.111, (P<0.05). The blood gas index of the observation group was significantly better than that of the control group. After 24h and 48h, the PaO2 of the observation group and the control group increased significantly, PaO2 decreased, FiO2 decreased, OI decreased, Compared to the difference was significant. Conclusion Neonatal respiratory distress syndrome with CPAP ventilator combined with ambroxol treatment, the effect is obvious, effective treatment of high blood gas recovery index is good, has a very high promotion value, should be vigorously promoted.
【关键词】CPAP呼吸机;氨溴索;新生儿呼吸窘迫综合症
【中图分类号】R441.8
【文献标识码】A
【DOI】10.3969/j.issn.1009-3257.2017.02.012
前言
临床中,治疗新生儿呼吸窘迫综合症的方法主要 是常规机械通气法,该治疗方法能够有效缓解患儿的 症状,氨溴索能刺激肺泡细胞合成并分泌肺表面活性 物质,但是却容易使新生儿出现不良反应。因此,本 科室通过CPAP呼吸机联合氨溴索治疗新生儿呼吸窘迫 综合症,取得了良好的效果,具体报道如下。
罕少疾病杂志
第24卷, 第 2 期
2019年11月
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