目的 研究单腔气管插管（single lumen endotracheal tube，SLET）在腔镜McKeown食管癌根治术中（minimally invasive McKeown esophagectomy，MIME）的可行性、安全性，胸段淋巴结清扫质量及手术并发症。方法 2016 年1月至2017年1月，共117例患者行腔镜McKeown食管癌根治术，其中单腔插管人工气胸下完成50例，双腔插管 （double lumen endotracheal tube，DLET）下完成67例。搜集两组患者的临床病理及围手术期资料，比较单腔组 与双腔组的手术时间、淋巴结清扫总数目、喉返神经旁淋巴结清扫数目及术后相关并发症。结果 单腔插管下行腔 镜McKeown食管癌根治术是可行且安全的，其中胸段手术时间、总手术时间单腔组均低于双腔组（P＜0.05），手术 出血单腔组低于双腔组(P＞0.05)，两组术后无重大并发症、围手术期均无死亡例数。单腔组与双腔组术后肺部并 发症、喉返神经损伤及吻合口瘘分别为3例(6％)、5例(7.4％)(P＞0.05)，6(12%)、5(7.4%)(P＞0.05)，6(12%)、 6(8.9%) (P＞0.05)，术后病理单腔组淋巴结清扫总数高于双腔组(P＞0.05)，单腔组左喉返神经旁淋巴结清扫总数 高于双腔组（P＜0.05）。结论 单腔气管插管下行腔镜McKeown食管癌根治术安全性与双腔气管插管相当，两组术 后吻合口瘘及喉返神经损伤差异无统计学意义，但单腔气管插管组左喉返神经旁淋巴结清扫质量、胸段手术时间及 总手术时间均优于双腔气管插管组。

Objective To analyze the feasibility, safety, thoracic lymph node resection and postoperative complications of single lumen and double lumen endotracheal tube respectively ,under minimally invasive McKeown esophagectomy(MIME). Methods Retrospective review of clinical pathology and perioperative data of 117 patients who had undergone minimally invasive McKeown esophagectomy from January 2016 to January 2017. Fifty patients who underwent MIME using single-lumen endotracheal tube (SLET) anaesthesia with CO2 artificial pneumothorax compared with 67 patients who underwent the same procedure with DLET intubation. Results MIME under SLET intubation is a feasible and safty procedure. The Duration of thoracic phase and the duration of total operation in double lumen group is longer than that of single lumen group (P<0.05). Bleeding volume in single lumen group is lower than that of double lumen group(P>0.05).And also the postoperative pulmonary related complications,recurrent nerve injury and anastomosis leak in single lumen group and double lumen group is 3cases(6%),5 cases(7.4%)(P>0.05),6 cases (12%), 5 cases (7.4%)(P<0.05), 6 cases (12%),6 cases (8.9%) (P>0.05) respectively. Single lumen group has more number of left recurrent laryngeal nerve lymph node resection than double lumen tube group(P<0.05). Conclusion In MIME, single lumen endotracheal tube intubation and double lumen endotracheal tube intubation airway management is both safe. There is no difference between two groups in postoperative Anastomosis leak and recurrent laryngeal nerve injury.In single lumen airway management group,the quality of the left recurrent laryngeal nerve lymph node resection,thoracic phase surgery duration and total operation duration were better than the double lumen endotracheal intubation group.