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·胸部疾病·

肺炎支原体肺炎患儿气道黏液栓形成的危险因素分析

作者:苑书华 谢小书

所属单位:河南省漯河市第二人民医院儿科 (河南 漯河 462000)

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摘要

目的 研究肺炎支原体肺炎(mycoplasma pneumoniae,MPP)患儿气道黏液栓形成的危险因素。方法 选取我院2011年 9月至2013年4月236例MPP患儿为研究对象,将患儿分为黏液栓组和对照组,黏液栓组132例,对照组104例,进行两 组临床资料、生化指标的比较和MPP患儿形成黏液栓危险因素Logistic回归分析。结果 通过黏液栓组和对照组的 比较,从性别、年龄、热程、胸腔积液、血白细胞数、中性粒细胞、C反应蛋白、乳酸脱氢酶、首次行纤维支气管 镜时间等9个可能因素中发现,年龄、热程、胸腔积液、C反应蛋白、乳酸脱氢酶水平与MPP患儿气道黏液栓形成有 关。结论 年龄、热程、胸腔积液、C反应蛋白、乳酸脱氢酶水平是MPP患儿气道黏液栓形成的危险因素,积极控制 危险因素可能有助于减少气道狭窄及闭塞的发生。

Objective To explore the risk factors for the formation of airway mucus plug in children with mycoplasma pneumonia (MPP). Methods From Sep. 2011 to Apr. 2013, a total of 236 MPP children who accepted treatments in our hospital were taken as the clinical research objects, and they were divided into mucus plug group(132 cases) and control group(104 cases). The clinical data and biochemical indexes of the two groups were compared, and the risk factors for the formation of airway mucus plug in children with MPP were analyzed by Logistic regression analysis. Results In 9 possible factors (gender, age, duration of fever, pleural effusion, white blood cell count, neutrophil, C-reactive protein, lactate dehydrogenase level and first bronchofibroscope examination time), age, duration of fever, pleural effusion, C-reactive protein and lactate dehydrogenase level were associated with the formation of airway mucus plug in children with MPP. Conclusion Age, duration of fever, pleural effusion, C-reactive protein and lactate dehydrogenase level are risk factors for the formation of airway mucus plug in children with MPP, and the positive control of risk factors may contribute to the reduction of airway stenosis and obstruction.

【关键词】肺炎支原体;气道黏液栓;危险因素

【中图分类号】R375+.2

【文献标识码】A

【DOI】10.3969/j.issn.1009-3257.2017.01.012

前言

肺炎支原体肺炎(mycoplasma pneumoniae,MPP) 是儿科呼吸系统常见病,以5~20岁最为常见[1]。预 防MPP患儿气道黏液栓的形成是临床医师面临的难 题,分析MPP患儿气道黏液栓的形成的危险因素,可 以帮助医师进行有效的预防和治疗,延缓病情的发 展,改善患儿的生存质量[2]。目前针对肺炎支原体肺 炎患儿气道黏液栓形成的危险因素的研究较少,因此 本文选取我院236例MPP患儿为研究对象,就研究结 果探讨肺炎支原体肺炎患儿气道黏液栓形成的危险 因素,以期为MPP患儿气道黏液栓的防治提供科学依 据。