·腹部疾病·
两种输卵管妊娠手术方式的临床对比分析
作者:高红艳1,2 孙光宇2 陈继明1 王 清1
所属单位:1.苏州大学附属第三医院妇科 (江苏 常州 213000) 2.江苏省常州市第七人民医院妇科 (江苏 常州 213000)
PDF摘要
目的 比较输卵管妊娠保守性手术和输卵管全切除术的临床应用价值与安全性。方法 回顾性分析2014年01月至2016 年06月常州市第七人民医院行手术治疗的67例输卵管妊娠患者的临床资料,其中26例行输卵管保守性手术,41例行 患侧输卵管全切除术。通过观察两组患者年龄、妊娠次数、输卵管妊娠部位、盆腔粘连、腹腔内出血量、术后血 HCG下降情况、持续性异位妊娠发生率、术后输卵管通畅及月经恢复情况,比较并分析两种手术方式的优缺点。结 果 保守性手术组年龄、妊娠次数及腹腔内出血量低于输卵管全切除术组(P<0.05);两组均以输卵管壶腹部妊娠为 主;所有患者经手术治疗后三天血HCG下降明显,输卵管全切除术组下降较保守性手术组明显(P<0.05);两组均无 一例发生持续性异位妊娠,其中保守性手术组术中有9例局部注射甲氨蝶呤(MTX)30mg;保守性手术组术后输卵管造 影有14例患侧输卵管通畅;术后两组患者月经恢复情况无明显差异(P>0.05)。结论 对于输卵管妊娠的手术治疗, 保守性手术和输卵管全切除术两种术式均是安全有效的。对年轻的或有意愿保留输卵管器官完整性的患者,如能早 期明确诊断,可行保留输卵管的保守性手术,术中局部MTX的注射可能有助于防止持续性异位妊娠的发生。
Objective To compare the clinical efficacy and security between conservative surgical treatment /salpingostom and salpingectomy for tubal ectopic pregnancy. Methods From January 2014 to June 2016, totally 67 patients with tubal ectopic pregnancy treated in the 7th People's Hospital of Changzhou were studied retrospectively. 26 patients were treated with salpingostom, while 41 patients were treated with salpingectomy. The following clinical parameters were compared, including age, number of conception, pregnancy sac position, pelvic adhesion, abdominal cavity blood loss, the decrease of serum HCG, the incidence of persistent ectopic pregnancy, tubal patency and menstruation recovery. Results In salpingostom group, the age, number of conception and volume of abdominal cavity blood loss are lower than in the salpingectomy group (P<0.05). Most tubal pregnancy in two groups are ampulla pregnancies, serum HCG drops obviously at the third day after surgery in two groups, more obvious in salpingectomy group (P<0.05). No case of persistent ectopic pregnancy in two groups, while nine patients in the salpingostom group were treated with tubal injection of methotrexate (MTX) 30 mg. Patients in the salpingostom group were treated with hystero-salpingography postoperative with 14 cases of the operation side were unobstructed. Menstruation recovery of patients in two groups has no obvious difference (P>0.05). Conclusion Both salpingostom and salpingectomy for tubal ectopic pregnancy could be effective and safe. For the younger or the patients intending to retain the integrity of the fallopian tube could be treated with salpingostom , and the tubal injection of MTX in the operation may help to prevent the occurrence of persistent ectopic pregnancy.
【关键词】输卵管妊娠;输卵管保守性手术;输卵管全切除术
【中图分类号】R714.22+1;R713.8
【文献标识码】A
【DOI】10.3969/j.issn.1009-3257.2016.06.013
前言
输卵管妊娠占异位妊娠的95%左右,严重地影响 着妇女的生殖健康[1],切除患侧输卵管是主要的手术 治疗方法,但这意味着患者将降低或部分丧失自然妊娠的能力,本文对比分析输卵管妊娠保留输卵管的保 守性手术和输卵管全切除术两种手术方式的临床效果 与安全性,以期为年轻有生育要求患者的临床处理提供一定的借鉴。
罕少疾病杂志
第23卷, 第 2 期
2019年11月
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