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论著-头颈部

MRI成像对宫颈癌诊 断及其周围侵犯判 断的价值*

作者:薛久华1 刘 婷1 柏 乐2

所属单位:1.陕西省西安市第一医院影像科 (陕西 西安 710002) 2.陕西省西安市长安区医院影像科 (陕西 西安 710100)

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摘要

目的 分析磁共振成像(MRI)对 宫颈癌的诊断及其周围侵犯的判断价 值。方法 收集我院妇产科近4年(2014年 3月-2018年3月)收治的71例宫颈癌患者 的术前MRI影像资料,所有患者均经手 术病理证实,以病理结果为参照,比较 MRI检查对宫颈癌原发灶及癌变累及范围 的显示效果,分析MRI检查对宫颈癌患 者的诊断及其侵犯范围的评估价值。结 果 MRI无法显示宫颈癌Ia期,评估宫颈癌 Ib期、II 期、III 期、IV期的准确性分 别为95.65%(66/69)、86.96%(60/69)、 94.20%(65/69)、100%(69/69),总准确 度为85.92%(61/71),与病理结果无显著 性差异(P>0.05);MRI对肿瘤累及阴道、 宫体、宫旁组织评估的准确率分别为 88.00%、72.73%、83.87%,灵敏度分别为 88.89%、82.35%、91.67%、特异度分别为 80.00%、40.00%、57.14%,阳性预测值分 别为97.56%、82.35%、88.00%,阴性预测 值分别为44.44%、40.00%、66.67%。结 论 MRI检查对宫颈癌原发灶及其侵犯范围 判断较准确,具有较高的临床价值,可将 其作为术前诊断及术后降期评估的有效依 据。

Objective To analyze the value of magnetic resonance imaging (MRI) in the diagnosis of cervical cancer and the judgment of surrounding invasion. Methods The preoperative MRI imaging data of 71 patients with cervical cancer admitted to our department of obstetrics and gynecology of our hospital in recent four years (from March 2014 to March 2018) were collected. All patients were confirmed by surgical pathology. The pathological results were taken as reference to compare the display effects of MRI towards the primary focus of cervical cancer and the extent of cancer involvement, and to analyze the estimated value of MRI in the diagnosis and invasion scope of patients with cervical cancer. Results MRI could not show stage Ia of cervical cancer, and the accuracies of MRI in evaluating stage Ib, stage II, stage III and stage IV of cervical cancer were 95.65% (66/69), 86.96% (60/69), 94.20% (65/69) and 100% (69/69) respectively, and the total accuracy was 85.92% (61/71), and there was no significant difference compared with the pathological results (P>0.05). The accuracies of MRI in the evaluation of tumor involving vagina, corpus and parametrium were 88.00%, 72.73% and 83.87% respectively, and the sensitivities were 88.89%, 82.35% and 91.67%, and the specificities were 80.00%, 40.00% and 57.14% respectively, and the positive predictive values were 97.56%, 82.35% and 88.00% respectively, and the negative predictive values were 44.44%, 40.00% and 66.67% respectively. Conclusion MRI examination has a relatively accurate judgment on the primary lesions and invasion scope of cervical cancer, and has high clinical value. And it can be used as an effective basis for preoperative diagnosis and postoperative assessment in clinic.

【关键词】宫颈癌;磁共振成像;周围组 织;分期;诊断

【中图分类号】R44;R73

【文献标识码】A

【DOI】 10.3969/j.issn.1672- 5131.2019.02.021

前言

宫颈癌是临床常见的妇科恶性肿瘤,是危害妇女健康与生命的主 要疾病,好发于中老年妇女,主要分布于30~35岁和50~55岁,发病 呈年轻化的趋势,占女性生殖系统恶性肿瘤的半数以上[1],提高宫颈 癌患者的早发现率及合理化早期治疗是改善宫颈癌预后的关键性因 素,目前宫颈癌的临床诊断及分期主要依据妇科专项检查及宫颈活检 细胞学检查,但其对肿瘤大小、位置、侵犯范围和深度判断均有所欠 缺[2]。随着影像技术的发展,出现了许多新的MR成像序列,越来越多 研究表明,磁共振成像(MRI)可多方位、多参数成像且软组织分辨率 高,对宫颈癌的敏感性高,是诊断宫颈癌分期的首选检查方法[3]。本 次研究以病理检查结果为参照标准,分析宫颈癌患者的MRI影像图像, 旨在探究MRI在宫颈癌疾病中的诊疗价值,以此寻求更切实可行的途 径,为节省诊疗时间、提高诊疗效果创造条件,现报告如下。