目的探讨核磁共振扩散加权成 像技术(Diffusion weighted imaging, DWI)在孕中晚期胎儿脑积水中的诊断价 值研究。方法 回顾性收集孕中晚期15例 胎儿脑积水和28例正常胎儿的影像资料 及临床资料，均行DWI扫描，分别测量脑 室周围额叶、颞叶、顶叶、枕叶白质、 基底节区、丘脑、脑干的表观弥散系数 (apparent diffusion coefficient, ADC)值，两组之间进行比较。结果 脑积 水组和正常对照组胎儿在孕周(P=0.965) 和孕妇年龄(P=0.981)上无明显统计学 差异。与对照组比较，脑积水胎儿额 叶(P=0.034)、顶叶(P=0.021)ADC值增 高，差异有统计学意义(P<0.05)。颞 叶(P=0.300)、枕叶(P=0.667)、基底 节(P=1.005)、丘脑(P=0.444)、脑干 (P=0.609)的ADC值, 差异均无统计学意 义。结论 核磁共振DWI技术可以提高胎儿 脑积水的诊断率，对产前诊断工作有重要 的价值和指导意义。

Objective To investigate the diagnostic value of diffusion weighted imaging (DWI) in fetal hydrocephalus in middle and late pregnancy. Methods Objective To analyze the imaging data and clinical data of 15 cases of hydrocephalus and 28 cases of normal fetus, and to measure the frontal lobe, temporal lobe, parietal lobe, occipital lobe, thalamus, basal Section of the brain, the brain stem of the ADC value, the hydrocephalus and normal fetal measurement results were analyzed. Results The hydrocephalus group and the normal control group fetus in gestational age (P=0.965) and pregnant women age (P=0.981) no significant difference. Compared with the control group, the hydrocephalus fetus frontal lobe (P=0.034), parietal lobe (P=0.021) ADC value increased statistically significant (P<0.05). ADC values of temporal lobe (P=0.300), occipital lobe (P=0.667), basal ganglia (P=1.005), thalamus (P=0.444) and brainstem (P=0.609) were not statistically different. Conclusion DWI sequence improve the diagnostic rate of fetal hydrocephalus, prenatal diagnosis has important value and guiding significance.