目的探讨核磁共振(MRI)T2 mapping成像技术在膝骨关节炎(OA)病情 评估中的作用。方法 选取2017年1月至 2018年2月在我院治疗的OA患者70例，其 中轻度OA患者21例，中度OA患者30例，重 度OA患者19例，同时选取健康志愿者60例 作为对照组，均给予MRI T2 mapping成像 扫描。结果 各OA亚组膝关节软骨T2值明 显高于对照组(P＜0.05)，其中重度OA组 T2值为(44.03±5.10)ms，明显高于轻度 OA组和中度OA组(P＜0.05)；根据Collins 病理学分级，其中0-Ⅰ级病变15例， Ⅱ-Ⅲ级病变32例，Ⅳ级病变13例；Ⅳ级 病变T2值为(50.24±3.96)ms，明显高于 0-Ⅰ级和Ⅱ-Ⅲ级(P＜0.05)；T2值与病情 程度、Collins分级呈正相关(rs=0.516和 0.560，P＜0.05)。结论 MRI T2 mapping 成像软骨定量分析可反映OA患者病情程度 以及病理分级情况，有助于膝关节软骨损 伤的监测及诊断。

Objective To investigate the role of magnetic resonance imaging (MRI) T2 mapping imaging in evaluating the condition of knee osteoarthritis (OA). Methods 70 cases of OA patients treated in our hospital from January 2017 to February 2018 were selected, including 21 cases of mild OA, 30 cases of moderate OA, 19 cases of severe OA, and 60 healthy volunteers as the control group, MRI T2 mapping imaging was given. Results The T2 value of the knee joint cartilage in the OA subgroups were significantly higher than that in the control group (P<0.05), and the T2 value of the severe OA group was (44.03±5.10) ms, which were significantly higher than that in the mild OA group and the moderate OA group (P<0.05). According to the pathological grading of Collins, there were 15 cases of grade 0-I, 32 cases of grade II-III, and 13 cases of grade IV lesions; The T2 value of grade IV lesions was (50.24±3.96) ms, which were significantly higher than that of grade 0 to grade I and grade II to III (P<0.05). The T2 value was positively correlated with the severity and Collins classification (rs=0.516 and 0.560, P<0.05). Conclusion MRI T2 mapping imaging quantitative analysis of cartilage can reflect the severity and pathological grading of OA patients, which is helpful for monitoring and diagnosis of cartilage injury in knee joint.