摘要
目的分析隆突性皮肤纤维肉瘤 (DFSP)患者15例的影像学检查情况。方法 回顾性分析我院15例DFSP患者影像学资 料,其中8例为CT检查,7例为MRI检查, 总结其影像学特征。结果 15例DFSP患者 肿瘤均位于皮肤和皮下脂肪层,均为单 发病灶,1例发生于后枕部,5例发生于胸 部,5例肿瘤发生于腰背部,2例发生于 臀部,2例发生于足底。肿瘤最长直径为 1.5-8.4cm,平均(5.22±1.47)cm。显微 镜下瘤细胞大小、形态较为一致(可见梭 形瘤细胞呈车辐状或纹状排列),间质内 可见大量胶原纤维和少量炎性细胞浸润, 免疫组化显示15例波形蛋白和CD34均为 (+)。8例行CT检查的DFSP患者中有6例平 扫显示病灶呈中等均匀密度,其中4例密 度略低。7例行MRI检查的DFSP患者中有3 例病灶T1WI呈等信号,T2WI呈不均匀高信 号;4例病灶T1WI呈稍低信号,T2WI、DWI 呈高信号,边界清晰,病灶增强扫描可见 均匀或不均匀明显强化。结论 DFSP患者 CT和MRI均有明显特征,益于定性诊断和 术前评估,具有一定临床应用价值。
Objective To analyze the imaging detection of 15 cases of patients with dermatofibrosarcoma protuberans (DFSP). Methods The imaging data of 15 cases of DFSP patients in our hospital were analyzed retrospectively. 8 cases were examined by CT and 7 cases were examined by MRI, and the imaging features were summarized. Results The tumors of 15 DFSP patients were located in the skin and subcutaneous fat layer and they were single lesions, including 1case in the posterior occipital part, 5 cases in chest, 5 cases in lower back, 2 cases in buttocks and 2 cases in planta. The longest diameter of tumor was 1.5-8.4cm with an average of (5.22±1.47) cm. Under the microscope, the size and shape of tumor cells were relatively uniform ( spindle-shaped tumor cells could be seen in a radial shape or streak arrangement), and a large number of collagen fibers and a small number of inflammatory cell infiltration were seen in the stroma, and immunohistochemistry showed vimentin and CD34 in 15 cases both were (+). Among 8 DFSP patients with CT, 6 cases showed moderate uniform density with 4 cases of a slightly lower density. Among DFSP patients with MRI, 3 cases showed equal signal on T1WI and uneven high signal on T2WI, and 4 cases showed slightly low signal on T1WI and high signal on T2WI and DWI with clear boundary, and enhancement scan showed uniform or non-uniformly marked enhancement. Conclusion Both CT and MRI have obvious features in DFSP patients, and they benefit qualitative diagnosis and preoperative evaluation, and have certain clinical application value.
【关键词】隆突性皮肤纤维肉瘤;CT; MRI
【中图分类号】R739.5
【文献标识码】A
【DOI】10.3969/j.issn.1672-5131.2018.11.045
前言
隆突性皮肤纤维肉瘤(DFSP)是一种病因和发病机制尚不明的肿 瘤,起源于真皮,发展缓慢,发生部位多在躯干、四肢,发病率较 低,患者多为中年人[1]。硬性斑块、肤色暗红、单结节或相邻多结节 是DFSP临床重要表现,症状能较早发现,多数患者均进行局部肿瘤切 除,但由于局部复发率高,还需进行二次手术[2-3]。为提高DFSP诊断准 确率,降低术后复发率,本次研究对我院15例DFSP患者影像学资料进 行分析。具体报告如下。
中国CT和MRI杂志
第16卷, 第 11 期
2018年11月
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