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子宫肌瘤子宫动脉栓塞术治疗前后MRI影像学特征分析

作者:郭玉生1 刘昱峰2 张莹莹1

所属单位:1.河南省鹤壁市人民医院妇产科(河南 鹤壁 458030) 2.河南省鹤壁市人民医院放射科(河南 鹤壁 458030)

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摘要

目的对比观察子宫肌瘤子宫动 脉栓塞术(UAE)治疗前后磁共振成像(MRI) 影像学特征。方法 回顾性分析2015年1 月-2017年7月于我院行UAE治疗的45例子 宫肌瘤患者临床资料,均于UAE治疗前行 临床检查及MRI检查,排除手术禁忌症, 并于治疗后1个月内行MRI复查,观察治疗 前后子宫肌瘤MRI信号特点及体积变化。 结果 经UAE治疗后,42例(93.33%)患者月 经恢复正常,另3例月经也有不同程度改 善,无闭经、子宫坏死等严重并发症出 现;45例患者中,单发肌瘤15例,多发30 例,共发现80个子宫肌瘤;治疗后共有68 个(85.00%)肌瘤T1WI序列明显升高,15个 (18.75%)肌瘤T2WI序列明显降低,,72 个(90.00%)肌瘤增强扫描强化程度明显 降低,13个(16.25%)肌瘤DWI序列明显降 低;治疗后肌瘤体积(32.48±21.20)cm3 较治疗前(69.48±30.74)cm3显著减小, 差异有统计学意义(t=8.862,P<0.05)。 结论 MRI是评价子宫肌瘤患者UAE治疗疗 效的重要影像学检查方法。

Objective To compare the magnetic resonance imaging (MRI) features of uterine fibroids before and after uterine artery embolization (UAE). Methods The clinical data of 45 cases of patients with uterine fibroids treated in our hospital from January 2015 -2017 July were retrospectively analyzed. All patients were given clinical examination and MRI examination before UAE so as to exclude surgical contraindications, and were given MRI recheck within 1 month after treatment. The MRI signal features and volume change of uterine fibroids were observed before and after treatment. Results After UAE, there were 42 cases (93.33%) with menstruation returned to normal, and 3 cases with different degrees of improvement, and there were no serious complications such as amenorrhea and uterine necrosis. Among 45 cases, 15 cases were single fibroids and 30 cases were multiple fibroids, and a total of 80 uterine fibroids were found. After treatment, T1WI sequences of 68(85%) fibroids were significantly increased, and T2WI sequences of 15(18.75%) fibroids were significantly reduced, and enhancement degrees of myoma enhanced scan of 72(90%) fibroids were significantly reduced, and DWI sequences of 13(16.25%) fibroids were significantly reduced. After treatment, the fibroid volume was significantly decreased compared with that before treatment [(32.48±21.20) cm3 vs (69.48±30.74) cm3 ] (t=8.862, P<0.05). Conclusion MRI is an important imaging method to evaluate the efficacy of UAE in patients with uterine fibroids.

【关键词】子宫肌瘤;子宫动脉栓塞术; 磁共振成像

【中图分类号】R737.33

【文献标识码】A

【DOI】10.3969/j.issn.1672-5131.2018.11.031

前言

子宫肌瘤由子宫平滑肌异常增生,周围肌纤维压迫形成假包膜 导致,患者伴有下腹疼痛、月经紊乱等症状,严重时可出现继发贫 血,系女性生殖系统疾病常见良性肿瘤,育龄期妇女中发病率高达 20%[1-2]。传统的子宫切除术虽然疗效明显,可有效改善患者症状,但 手术创伤极大,术后患者丧失生育能力,卵巢功能减退,直接影响患 者生活质量。子宫动脉栓塞术(UAE)是一种手术创伤小、操作简便、可 保留子宫的微创疗法,现已被广泛用于临床治疗子宫肌瘤,患者接受 度高。近年来国内外多项研究显示[3-4],磁共振成像(MRI)可清晰显示 子宫肌瘤位置、体积等形态学表现,还可利用弥散加权成像(DWI)技术 从病灶组织构成方面评价,是子宫肌瘤临床常用的影像学检查方法。 本研究对比子宫肌瘤患者UAE治疗前后的MRI影像学特征,旨在探究MRI 检查在子宫肌瘤UAE治疗疗效评估中的应用价值,现报道如下。